A Custom Proteomics Solution Bridging Discovery and Targeted Assays for Drug Development

This case study from Inoviv demonstrates how InoKey, an end-to-end proteomics solution, formulated a high-throughput LC-MS/MS workflow to stratify patients' plasma proteomes in response to SARS-CoV-2 infection, informing an assay that outperformed other severity score models and predicted patient outcomes for a streamlined clinical treatment escalation strategy.

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The Benefits of Using Cellulose Nanobeads Over Colloidal Gold in Lateral Flow Assays

This white paper from Asahi Kasei discusses the technical and practical advantages of NanoAct cellulose nanobeads compared to colloidal gold in lateral flow assays, with a comprehensive performance evaluation highlighting enhanced sensitivity and comparative benefits in antibody consumption.

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Case Study: The Role of Premium Reference Materials in Precision Oncology Test Validation

This white paper explains how working closely with LGC Clinical Diagnostics ensures that Biofidelity is provided with the high-quality, bespoke next-generation sequencing reference materials that the company needs to validate its technology for translation into clinical practice.

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The Importance of Rapid Testing for Syphilis

In this white paper from OraSure Technologies, Jeffrey Klausner, professor of medicine and public health at the Keck School of Medicine at the University of Southern California, describes how rapid treponemal testing offers highly accurate results in just 10 minutes, and how people who test positive can get antibiotic treatment immediately.

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Rapid Room Temperature Protein Digestion for Mass Spectrometry

This application note from Tecan describes the use of Resolvex Prep’s customizable μSPEed-Cxyl microreactor cartridges for rapid protein digestion at ambient temperature of bovine serum albumin, the most common reference standard used in proteomic system compliance checks, and cytochrome C, frequently used as a model protein for molecular evolution experiments.

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Development and Validation of Blood Tumor Mutational Burden Reference Standards

This white paper from LGC Clinical Diagnostics discusses the development of contrived bTMB reference materials using DNA from tumor cell lines and donor matched lymphoblastoid cell lines to support calibration and alignment across different laboratories and bTMB platforms.

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